Guaiacum (/ˈɡwaɪ.ə.kəm/[3][4]), sometimes spelled Guajacum, is a genus of flowering plants in the caltrop family Zygophyllaceae. It contains five species of slow-growing shrubs and trees, reaching a height of approximately 20 m (66 ft) but usually less than half of that. All are native to subtropical and tropical regions of the Americas and are commonly known as lignum-vitae, guayacán (Spanish), or gaïac (French).[5] The genus name originated in Taíno, the language spoken by the native Taínos of the Bahamas; it was adopted into English in 1533, the first word in that language of American origin.[6]
Members of the genus have a variety of uses, including as lumber, for medicinal purposes, and as ornamentals. The trade of all species of Guaiacum is controlled under CITES Appendix II.[7]
Guaiacum officinale is the national flower of Jamaica,[8] while Guaiacum sanctum is the national tree of the Bahamas.[9]
The genus is famous as the supplier of lignum vitae, which is the wood of several species in the genus.[citation needed] It is the fourth-hardest variety of wood as measured by the Janka hardness test, requiring a force of 4,500 lbf (20,000 N) to embed a steel ball 0.444 in (1.13 cm) in diameter half that distance into the wood.[10]
The Spanish encountered guaiacum wood when they conquered San Domingo in the sixteenth century. It was soon brought back to Europe, where epidemic syphilis had been raging for nearly a century. Gum guiacum quickly acquired a reputation as a cure for syphilis,[11] a practice Benvenuto Cellini records in his memoirs.[12] Thomas Nashe referred to its supposed medical properties in his tract Nashe's Lenten Stuff, alluding to the exotic sound of the word itself: "Physicians deafen our ears with the honorificabilitudinitatibus of their heavenly panacaea, their sovereign guiacum."[13] The detailed engraving, Preparation and Use of Guayaco for Treating Syphilis, published by Philips Galle after a design by the Flemish artist Jan van der Straet, depicts four servants preparing a concoction of gum guiacum for their wealthy master under the supervision of a physician.[14] Paracelsus, the famous if controversial Swiss physician, disputed the effectiveness of this treatment and was censured for his criticism.[citation needed]
Gum guaiacum was used to stimulate menstruation; in a 1793 Virginia court case, Martha Jefferson Randolph testified that she had provided gum guaiacum to a female relative to "produce an abortion",[15] suggesting that it was also used as an abortifacient. In A Treatise of the Materia Medica (1789), Scottish physician William Cullen noted: "Several physicians have apprehended mischief from the use of the guaiacum in a spirituous tincture."[16][17]